Modern Australian
Men's Weekly

.

PolyU develops ultrasensitive and portable detection sensor for rapid, easy and low-cost COVID-19 antibody test

HONG KONG SAR - Media OutReach - 26 May 2022 - As the outbreak of the COVID-19 pandemic has continued for over two years, a fast and accurate antibody detection method can help assess the antibody content of the human body, as well as provide reference data for healthcare departments to formulate appropriate vaccination measures.

In the long run, the antibody content data can also contribute to epidemiological studies and vaccine development. In view of this, a research team from the Department of Applied Physics of The Hong Kong Polytechnic University (PolyU) has successfully developed an ultrasensitive and portable COVID-19 antibody detection sensor based on organic electrochemical transistor (OECT) technology. Fast and easy-to-use, the sensor is designed for testing the antibody levels of people who have either received vaccination or have been infected with the virus.

1.jpg
A research team from the Department of Applied Physics of PolyU has successfully developed an ultrasensitive and portable COVID-19 antibody detection sensor. Present at the press conference were Professor Feng YAN (left), Professor of the Department of Applied Physics, PolyU; and Dr Helen LAW (right), Associate Professor of the Department of Health Technology and Informatics, PolyU.

Currently, the detection of SARS-CoV-2 immunoglobulin G (IgG) is based on enzyme-linked immunosorbent assay (ELISA) testing of serum samples. Such testing requires the use of bulky medical equipment and can only be performed in hospitals or specialised testing laboratories. It takes about two days to acquire the test results and the cost is high. There is an alternative rapid method based on lateral flow immunoassay (LFIA) testing. However, the sensitivity of this method is lower and incapable of showing the actual level of antibody content.

2.jpg
The COVID-19 antibody detection sensor developed by the PolyU research team comes with an array of advantages – it is highly sensitive, portable, rapid, easy-to-use and low-cost.

The COVID-19 antibody detection sensor developed by the PolyU research team comes with an array of advantages – it is highly sensitive, portable, rapid, easy-to-use and low-cost. The testing procedure is very simple. First, turn on the sensor and connect it to the smartphone app via Bluetooth. Then, drop 10uL of a saliva (or serum) sample on the transistor test area to allow the antibody-antigen reaction. Wait for five minutes, then extract the saliva sample and add an electrolyte drop on the test area. Press the button on the smartphone app to start the test. After about 20 seconds, the app will display the antibody content level of the saliva sample.

The whole detection process takes less than six minutes and the cost per test is only about HK$10.

The antibody detection sensor can test the concentration of antibodies from lower than 10fM to higher than 100nM. The detection limit satisfies the needs of exquisite analytical sensitivity for saliva.

Principal Investigator of the study, Professor Feng YAN, Professor of the Department of Applied Physics at PolyU, said, “Our research team developed a novel technology by applying voltage pulses on the gate of the sliced transistor to accelerate the incubation process resulting in a significant decrease in the overall detection time. Since the detection process is non-invasive, using only saliva instead of blood, self-sampling is highly possible. Moreover, the operation and result reading are very simple with the use of a smartphone, and hence the sensor is suitable for instant detection and large-scale screening scenarios.”

The next plan of the research team is to apply for funding for clinical studies in collaboration with different medical and testing institutions. The research team expects that the novel device can be commercialised as soon as practicable and applied for antibody detection of other viruses, helping to fight diseases and making contributions to epidemiological studies and vaccine development.

#PolyU

Understanding Trade Insurance: Essential Protection for Businesses

Image by Drazen Zigic on Freepik In the current economic environment, trade insurance is an important element for companies trading both locally an...

Choosing the Right Timber for External Cladding

Timber cladding is one of those finishes that pulls double duty: it makes a building look warm and welcoming, and it quietly shields the frame from ...

Top Services Offered by Diesel Mechanics in Brisbane

Keeping a diesel vehicle running at its best takes more than the occasional oil change. When you invest in regular specialist care, you protect the ...

Top 5 Benefits of Hiring Professional House Removalists

Moving day should feel like the start of a new adventure, not the end of your patience. Yet once the settlement papers are signed and the champagne ...

Navigating the Digital Landscape: Managed IT Solutions and IT Services in Townsville

As technology advances at an unprecedented pace, companies must adapt to embrace the transformation ahead. With an evolving technology landscape, mana...

Types of Catering You Should Consider for Your Next Event

Choosing the right type of catering service can elevate your event from ordinary to unforgettable. Whether it’s an elegant wedding, corporate func...

Understanding the Benefits of Split System Installation for Your Home

Climate control is essential to maintaining comfort in your home, especially during the extreme temperatures that many regions face. Whether you’r...

Best Aluminium Window Sliding Designs for Natural Light and Airflow

Bringing natural light and airflow into a space is one of the most efficient ways to create a healthy and comfortable home. In Sydney and across Aus...

Maximising Operational Efficiency: Electric Winch Hire Australia and Hydraulic Power Pack Hire Solutions

Image by jcomp on Freepik From urban construction sites and remote mining operations to coastal maritime facilities, specialised equipment solutio...

Navigating the System: Your Guide to Support Finding Work with a Disability Around Melbourne

Image by freepik Finding the right job can be a challenge for anyone, but it can feel particularly daunting when you're also navigating life with a ...

Say Goodbye to Draughts and Hello to Savings: Your Guide to Perth Window Replacement

Image by prostooleh on Freepik Are your windows looking worse for wear? Are you paying a hefty power bill due to sneaky draughts and poor insulation...

How to Choose the Right Horse Trailer for Your Riding Needs

Many horse owners travel long distances for riding lessons, competitions, or to move horses between properties. Having a safe and reliable trailer i...

Sydney Turf Installer for Instant Green Lawns and Long-Term Performance

Having a green lawn at home makes everything look better. Whether it’s the front yard, backyard, or a small patch beside the driveway, people in S...

Designing Better Living Spaces: Why New Kitchens in the Blue Mountains Are in High Demand

The Blue Mountains region is seeing a steady rise in home upgrades. According to recent housing data, kitchen renovations remain one of the most req...

The Role of Packaging Manufacturers in Reducing Supply Chain Costs

In today’s fast-paced logistics and distribution landscape, businesses are under constant pressure to optimise operations and reduce expenses. One...

Customising Roller Shutters for Warehouses, Factories, and Logistics Hubs

In today’s fast-paced industrial and commercial environments, security, functionality, and efficiency are paramount. Whether you manage a busy log...

Top Fire Hazards in Commercial Buildings and How to Avoid Them

When it comes to protecting lives, assets, and business continuity, fire safety should be at the forefront of every commercial property owner’s ri...

Refillable Bottles and the Role of Reusable Caps in a Sustainable Packaging Future

As industries across the globe strive to reduce environmental impact, refillable bottles and reusable caps are emerging as champions of sustainable ...