Modern Australian
The Times Real Estate

.

Tick-tock – for healthy mums and kids, dad’s age counts

  • Written by Sarah Robertson, Professor and Director, Robinson Research Institute, University of Adelaide

Women are regularly reminded of their ticking biological clock. It turns out men should also pay attention to age when it comes to having a family.

A new study published today in the British Medical Journal provides persuasive evidence that children – and pregnant mums – are more likely to have health problems when dads are older.

Men’s fertility declines with age, but not as sharply as women’s. Men can continue to father children into later life – as Mick Jagger and other celebrity fathers demonstrate.

But it takes longer to get pregnant. One study in European men showed a 50% lower chance of conceiving after a year of trying at age 35, compared with men younger than 25.

Plus, women with partners age 35 and older may be more likely to experience miscarriage than those with younger partners.

Read more: Most men don't realise age is a factor in their fertility too

Higher odds of premature birth

The latest study shows that the chances of pregnancy and birth problems are also increased when dads are older.

Researchers at Stanford University in California analysed data on all 40 million live births in the United States between 2007 and 2016 to look at how paternal age affects outcomes for the infant and the mother.

As the father’s age increased, so did the chances of the infant being born prematurely, having a low birth weight, or requiring medical intervention after delivery, such as assisted ventilation, admission to neonatal intensive care, or antibiotics.

Tick-tock – for healthy mums and kids, dad’s age counts It takes dads over 35 longer to conceive than those under 25. Katie Emslie

When fathers were aged 45 years or more, their children had 14% higher odds of being born premature (less than 37 weeks) and their babies had a 14% greater risk of low birth weight (less than 2.5kg) than when fathers were aged 25 to 34 years.

Infants with fathers aged 45 years or more were also 14% more likely to be admitted to a neonatal intensive care unit, and 18% more likely to have seizures.

If the father was 55 years or older, newborns also tended to score less well on the Apgar test used to assess the health of a child at birth.

These effects were present after adjusting for the mother’s age, smoking, race, education, and number of prenatal visits.

Future risk of disease

These latest findings add to earlier studies showing older age in fathers is linked with a variety of health conditions affecting the offspring.

Scientists in Denmark have calculated the chances of congenital problems linked to older fatherhood and show that several conditions become more prevalent. These include rare developmental conditions such as achondroplasia (dwarfism) and cleft palate.

Cancer rates among offspring also seem to rise as dads become older.

Read more: Why men need to think about their fertility too

Arguably the most concerning impact is on neurodevelopment and mental health. Offspring of older fathers have an increased risk of schizophrenia, mental retardation, and autism spectrum disorders.

The risk of schizophrenia increases by 47% when fathers are over 45 years old.

The rate of childhood autism increases by 80% when dads conceive after age 45.

Sign up for the newsletter

Tick-tock – for healthy mums and kids, dad’s age counts Sign up to Thrive, a weekly dose of evidence to help you live well. So what’s going on? Changes in the sperm of older men are likely to contribute. The number of defective sperm containing DNA mutations increase steadily every year as men age. These arise as exposure to radiation, environmental toxins, alcohol and smoking take their toll. Ageing itself results in less testosterone and a decline in the number and function of testicular cells. Tick-tock – for healthy mums and kids, dad’s age counts Most older dads won’t have fertility problems. Picsea However, genetics isn’t the full explanation. In particular, increased risk of psychiatric illness doesn’t seem to be due to spontaneous mutations in sperm DNA. While mutations contribute, they account for only about 10% to 20% of the effect. Another possibility is that genetic risk factors naturally more prevalent in men destined to be older fathers might be passed on to their offspring, rather than new mutations. Mothers also at risk The latest data showed negative effects of delayed fatherhood not just for the infants, but also the pregnant mothers. The risk of gestational diabetes for pregnant women increased in line with the age of the father, with women carrying the child of a man aged 55 years or older having a 34% higher odds of gestational diabetes. The researchers estimate that around 13% of premature births and 18% of gestational diabetes in pregnancies associated with older fathers were attributable to the advanced age of the father. Read more: What's the point of sex? It's communication at a biological level This is hard to reconcile with a genetic explanation. Other biological effects of seminal fluid on pregnancy health may be to blame. The female immune system responds to seminal fluid by generating immune tolerance, which protects against inflammatory exposures that can harm the fetus. Human seminal fluid contains signals known to stimulate the female immune response, but it’s not yet proven whether these factors decline as men age. What does this all mean for men contemplating fatherhood? Most older dads don’t have fertility problems and can father babies without serious physical or developmental problems. Overall, the father’s age is substantially less important than the mother’s age, and generally the pregnancy disorders and infant health problems are rare. So the current research evidence doesn’t justify dissuading older men from becoming fathers. Tick-tock – for healthy mums and kids, dad’s age counts The children of most older dads will be fine. Brittany Simuangco But the medical community must do a better job of communicating to couples an understanding of the risks of advanced paternal age. Most importantly, we must include men in conversations about pregnancy planning and preconception care, to ensure all couples have the best chance of raising a healthy child.

Authors: Sarah Robertson, Professor and Director, Robinson Research Institute, University of Adelaide

Read more http://theconversation.com/tick-tock-for-healthy-mums-and-kids-dads-age-counts-105962

The Best Nail Art for Short Nails

Short nails often get overlooked in the world of nail art, but they’re actually the perfect canvas for stylish, sophisticated designs. Whether you...

How Much Does a Skip Bin Cost? Skip Bin Prices, Sizes & What Influences the Price

Regardless of whether you're renovating a house. You are tidying up your backyard, or running a construction site. Chances are you'll require a skip...

Panoramic Elevators: Combining Functionality with Aesthetic Appeal

In the evolving world of building design, the demand for architectural features that are both practical and visually striking continues to rise. One...

No Dig, No Drama: Sydney Pipe Relining Explained

You know that feeling when water starts pooling where it shouldn't? Or received a quote for pipe repairs that made your eyes water? Let's chat about...

The SEO Benefits of AI-Optimized Landing Pages: Smarter Metadata, Faster Load Times

Landing pages are integral to the conversion funnel in digital marketing. Yet, when SEO works well to drive traffic to the landing page, it's just a...

How to Reduce Turbo Lag with an Upgraded Mazda BT-50 Exhaust System

Are you struggling with turbo lag affecting your driving experience?  Did you know upgrading your Mazda BT-50 exhaust system could be the key to u...

How to Segment Email Lists Based on Content Engagement (Not Just Demographics)

Email segmentation generally refers to age, location, gender demographic, and conventional elements. While this could be helpful information, it doe...

6 Qualities to Look for in Local Caravan Dealers

If you're searching for reliable caravan dealers in Campbellfield, it's essential to choose a dealer that offers quality products, excellent custome...

How to Repair a Faema Coffee Machine: A Practical Guide for Coffee Lovers

Introduction If you’re the proud owner of a Faema coffee machine, you already know that it’s more than just a kitchen appliance — it’s a vi...

Smart Health Decisions in Your 30s, 40s, and 50s: The Ultimate Prevention Guide

Making informed health decisions becomes increasingly important as we navigate through different life stages. What may have seemed unimportant in our ...

Sydney’s Electricians Helping Cut Business Costs

Running a business in Sydney isn’t cheap. Between rent, wages, equipment, insurance, and endless operational costs, it’s no wonder business owne...

Can Air Conditioning Help with Allergies and Asthma?

Living with allergies or asthma can make everyday environments feel challenging—especially during certain seasons or in homes where dust, pollen, ...

A Fast Charging Power Bank and Wireless Power Bank: The Future of Power Bank Technology

As the use of mobile devices grows, so does the demand for better, more efficient, faster, and more imaginative methods to power them. Previously re...

How to Extend the Lifespan of Your Power Bank: An Overview

Power banks are vital for ensuring your devices are powered while on the go, especially when on the move, outdoors, or during emergencies. They prov...

What is a Power Bank and How To Choose One

In a world filled with gadgets running out of battery is a real issue. This is where power banks can come in useful. They're portable, they hold pow...

Portable Chargers: How They Work & Essential Tips to Extend Battery Life

Portable chargers (also known as power banks) are essential accessories that keep your devices powered up while on the go — be it outdoor activiti...

How Artificial Tulip Displays Enhance Your Home’s Aesthetic

Artificial tulip displays have grown to be a common option for improving interior decor because of their exquisite look and long-lasting quality. Th...

The Psychology of Relationships: How Therapy Can Strengthen Bonds

Relationships require effort, understanding and communication. Couples and individuals can have better relationships with the assistance of therap...