Modern Australian
Men's Weekly

.

New antibiotic drug developed by HKU Chemistry research team approved for clinical trials in humans

HONG KONG SAR - Media OutReach - 11 October 2023 - A new antibiotic drug developed by a research team led by Professor Li Xuechen from the Department of Chemistry at The University of Hong Kong (HKU) has recently gained approval from the authorities to undergo clinical trials in the Mainland.



Professor Xuechen Li
Professor Xuechen Li

The new drug, which has taken the research team ten years to develop and is named Kynomycin, received the "Notice of Approval for Drug Clinical Trials" from the National Medical Products Administration of China to be tested in human subjects.

The new antibiotic drug targets complex skin and soft tissue infections (cSSTI) caused by bacteria. It is a new type of cyclic lipopeptide category 1 drug with a novel chemical structure. The patent is licensed to a pharmaceutical company in the Mainland by HKU's Technology Transfer Office through the University's wholly-owned subsidiary, Versitech Limited.

Skin and soft tissue infections are very common bacterial infectious diseases in clinical practice, often leading to emergency visits and hospitalisation. With the emergence of clinically resistant strains and the development of bacterial pathogens that are resistant to antibiotics, treatment options have become increasingly limited.

The development of this drug aims to improve the safety and efficacy of cyclic lipopeptide antibiotics and provide a new choice for clinical treatment. After obtaining approval for this clinical trial, the drug still needs to undergo Phase I, II, and III clinical trials and be evaluated and approved by the National Medical Products Administration before it can be produced and marketed.

The research of Prof Li Xuechen lies in the interface of synthetic chemistry, medicinal chemistry and biology, spanning from innovative synthetic method development to biological studies and drug discovery, with the ultimate aim to develop novel therapeutics.

Professor Li was honoured in May this year with the Contribution Award in Carbohydrate Chemistry by the Chinese Chemical Society (CCS), recognising his pioneering contributions in precision chemical synthesis, chemical biology, and the development of therapeutic glycoconjugates of glycoproteins and bacterial complex carbohydrates. He has also been awarded the 2023/24 Research Grants Council Senior Research Fellowship, which funds his continued research on the synthesis and application of chemically synthesised proteins.

Hashtag: #HKU

The issuer is solely responsible for the content of this announcement.

About Technology Transfer Office, HKU

The Technology Transfer Office (TTO) manages the use of HKU's intellectual property assets by providing patenting, licensing and other commercialisation support to the University's researchers and inventors. Acting as the bridge linking HKU to society in the area of technology commercialisation, TTO helps industries and businesses to access HKU's powerhouse of knowledge, innovation and expertise through close collaboration. Website: .

About Versitech Limited

Versitech Limited is the commercial arm of HKU. It was established in 1994 as a wholly-owned subsidiary of the University and is incorporated as a non-profit company with prominent business people on its Board of Management. Versitech negotiates, executes and manages commercial business contracts and agreements on behalf of the University. To serve business and community needs, Versitech undertakes the commercialisation of HKU innovations and technologies through licensing, the creation of start-ups or collaboration, and engages in contract research and consulting in conjunction with HKU researchers. Website: .

Your Guide to Finding the Right GP: What Perth City Doctors Offer Today

Choosing a General Practitioner (GP) is one of the most important health decisions you’ll make. Luckily, Perth’s vibrant CBD now hosts a new ge...

Why Every Mining Operation Needs a Robust Safety Management System

Mining is one of the backbones of the Australian economy, particularly in Western Australia. Back in 2019-20, mining contributed 10.4% of Australiaâ...

Australian Classic Literature Enjoys Resurgence

Welcome back to the good old days of storytelling! As the modern world becomes increasingly more demanding, returning to childhood favourites offers...

Building a Governance Model for Headless Content Management at Scale

Image by pch.vector on Freepik There's never been a better time to implement a headless content management system (CMS) to gain the flexibility and ...

Understanding Trade Insurance: Essential Protection for Businesses

Image by Drazen Zigic on Freepik In the current economic environment, trade insurance is an important element for companies trading both locally an...

Choosing the Right Timber for External Cladding

Timber cladding is one of those finishes that pulls double duty: it makes a building look warm and welcoming, and it quietly shields the frame from ...

Top Services Offered by Diesel Mechanics in Brisbane

Keeping a diesel vehicle running at its best takes more than the occasional oil change. When you invest in regular specialist care, you protect the ...

Top 5 Benefits of Hiring Professional House Removalists

Moving day should feel like the start of a new adventure, not the end of your patience. Yet once the settlement papers are signed and the champagne ...

Navigating the Digital Landscape: Managed IT Solutions and IT Services in Townsville

As technology advances at an unprecedented pace, companies must adapt to embrace the transformation ahead. With an evolving technology landscape, mana...

Types of Catering You Should Consider for Your Next Event

Choosing the right type of catering service can elevate your event from ordinary to unforgettable. Whether it’s an elegant wedding, corporate func...

Understanding the Benefits of Split System Installation for Your Home

Climate control is essential to maintaining comfort in your home, especially during the extreme temperatures that many regions face. Whether you’r...

Best Aluminium Window Sliding Designs for Natural Light and Airflow

Bringing natural light and airflow into a space is one of the most efficient ways to create a healthy and comfortable home. In Sydney and across Aus...

Maximising Operational Efficiency: Electric Winch Hire Australia and Hydraulic Power Pack Hire Solutions

Image by jcomp on Freepik From urban construction sites and remote mining operations to coastal maritime facilities, specialised equipment solutio...

Navigating the System: Your Guide to Support Finding Work with a Disability Around Melbourne

Image by freepik Finding the right job can be a challenge for anyone, but it can feel particularly daunting when you're also navigating life with a ...

Say Goodbye to Draughts and Hello to Savings: Your Guide to Perth Window Replacement

Image by prostooleh on Freepik Are your windows looking worse for wear? Are you paying a hefty power bill due to sneaky draughts and poor insulation...

How to Choose the Right Horse Trailer for Your Riding Needs

Many horse owners travel long distances for riding lessons, competitions, or to move horses between properties. Having a safe and reliable trailer i...

Sydney Turf Installer for Instant Green Lawns and Long-Term Performance

Having a green lawn at home makes everything look better. Whether it’s the front yard, backyard, or a small patch beside the driveway, people in S...

Designing Better Living Spaces: Why New Kitchens in the Blue Mountains Are in High Demand

The Blue Mountains region is seeing a steady rise in home upgrades. According to recent housing data, kitchen renovations remain one of the most req...